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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDZD2 All Species: 3.94
Human Site: S2373 Identified Species: 10.83
UniProt: O15018 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15018 NP_835260.2 2839 301641 S2373 K P P I G R R S S G S I V S G
Chimpanzee Pan troglodytes XP_526957 2443 258187 T2026 A K S P S I M T L T I S R Q N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536512 2601 274017 G2184 K K E G S G L G F T V A G G T
Cat Felis silvestris
Mouse Mus musculus O54824 1322 141416 N905 S M S T T F P N S S E V R D P
Rat Rattus norvegicus Q9QZR8 2766 293871 Q2323 E A S S L L P Q M T K S P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519211 1909 204581 P1492 V V S A A G R P A R D S Q S A
Chicken Gallus gallus XP_424994 2494 266916 T2077 G T P S P A D T V A K L P I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697544 1714 185798 S1297 R E A S G K M S I G D E I V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121687 1433 154933 S1016 D E G S F G R S K S Q M S L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.7 N.A. 51.1 N.A. 22.5 68.2 N.A. 23.9 32 N.A. 22.7 N.A. N.A. 20.4 N.A. N.A.
Protein Similarity: 100 85.1 N.A. 60.5 N.A. 32.4 76.5 N.A. 37.5 47.5 N.A. 35.3 N.A. N.A. 32.5 N.A. N.A.
P-Site Identity: 100 0 N.A. 6.6 N.A. 6.6 6.6 N.A. 13.3 6.6 N.A. 20 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 6.6 N.A. 6.6 N.A. 20 13.3 N.A. 20 20 N.A. 40 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 12 12 12 12 0 0 12 12 0 12 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 12 0 0 0 23 0 0 12 0 % D
% Glu: 12 23 12 0 0 0 0 0 0 0 12 12 0 0 12 % E
% Phe: 0 0 0 0 12 12 0 0 12 0 0 0 0 0 0 % F
% Gly: 12 0 12 12 23 34 0 12 0 23 0 0 12 12 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 12 0 0 12 0 12 12 12 12 0 % I
% Lys: 23 23 0 0 0 12 0 0 12 0 23 0 0 0 0 % K
% Leu: 0 0 0 0 12 12 12 0 12 0 0 12 0 12 0 % L
% Met: 0 12 0 0 0 0 23 0 12 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 12 % N
% Pro: 0 12 23 12 12 0 23 12 0 0 0 0 23 0 12 % P
% Gln: 0 0 0 0 0 0 0 12 0 0 12 0 12 12 0 % Q
% Arg: 12 0 0 0 0 12 34 0 0 12 0 0 23 0 0 % R
% Ser: 12 0 45 45 23 0 0 34 23 23 12 34 12 34 23 % S
% Thr: 0 12 0 12 12 0 0 23 0 34 0 0 0 0 23 % T
% Val: 12 12 0 0 0 0 0 0 12 0 12 12 12 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _